Field of Study
    • Spermatology & Andrology
      • Sperm Induction of acrosome reaction in spermatozoa accelates development of fertilized human oocyte after intracytoplasmic sperm injection. (52th ASRM, 1996).
      • Identification of round spermatid from testis biopsy and its application in human ART program. (10th World Congress on IVF & ART, 1997)
      • Detailed semen analysis and ICSI in azoospermia-like infertile patients. (53th ASRM, 1997)
      • AZF and Microdeletion Microdeletions of Y Chromosome in Korean Male Infertility Patients (5th ICA,1997)
      • Evaluation of spermatogenesis by DAZ and protamine-2 gene in human testis biopsy (5th ICA, 1997)
      • The Incidence of microdeletion and the frequency of AZFa, b, c deletion in male infertility patients. (53th ASRM, 1997)
      • ART Application of ICSI or ROSI by testicular biopsy in non-obstructive azoospermia.(53th ASRM, 1997)
      • Analysis of fertilization, embryonic development and pregnancy rates after ICSI using spermatozoa obtained from fresh or frozen-thawed testicular tissues (54th ASRM, 1998)
      • Sperm DNA fragmentation assay: Comet assay (CERM 2011),
      • Halosperm assay (KSRM 2012),
      • Sperm protamine deficiency assay: CMA3 assay and Aniline blue assay (KSRM 2012)
        • Oogenesis and Folliculogenesis
          • Oocytes Production of mature oocyte from frozen-thawed primordial follicular oocyte by reconstruction with cytoplasm of full grown germinal vesicle(GV)-stage oocyte. (55th ASRM, 1999)
          • Follicle In vitro Growth of Primordial Follicular Oocyte in the Frozen-Thawed Ovarian Tissue of Neonatal Mouse (54th ASRM, 1998)
          • Steroidogenesis in the Frozen-Thawed 18 Weeks Human Fetal Ovarian Tissues Cultured In Vitro (54th ASRM, 1998)
          • TGF βI and TGF βII were detected from fresh 18 weeks fetal ovarian tissue in human.
          • Ovarian Endocrinology Expression of Melatonin receptor gene in mouse gonad. (54th ASRM, 1998)
          • The synergistic effect of VIP and FSH in vitro on the expression of FSH receptor gene in human fetal ovary. (55th ASRM, 1999)
          • Expression of receptor genes for gonadotrophins and estrogens, and biosynthesis of estrogen in mid-gestational stage of human ovarian tissues. (55th ASRM, 1999)
          • Expression and localization of cell cycle-related proteins and receptor genes for gonadotropins, estrogen, and aromatase in human fetal ovaries; a preliminary study (International Workshop on Early Folliculogenesis and Oocyte Development,1999)
          • The effect of vasoactive intestinal peptide on estradiol biosynthesis in human fetal ovarian tissue in vitro.(International Workshop on Early Folliculogenesis and Oocyte Development 1999)
            • Embryogenesis, Hatching and Implantation
              • Embryology Regulation of embryonic genome activation and compaction by the transfer of cytoplasm transfer with inhibitors of protein synthesis or protein kinase in mouse. (32th SSR, 1999)
              • Hatching Biochemical Assisted Hatching by Proteases Increased Pregnancy Rates in Human IVF-ET Program (1996' ASRM)
              • Application of biochemically assisted hatching(BAH) by proteases in human assisted reproductive technology program. (53th ASRM, 1997)
              • Improvement of pregnancy and implantation rate by biochemical assisted hatching in human IVF-ET. (11th World Congress on IVF & Hum Reprod Genet, 1999)
              • Outcome of Biochemical Assisted Hatching in 1068 IVF-ET Cycles Using Pronase in Human Assisted Reproductive Technology. (11th World Congress on IVF & Hum Reprod Genet, 1999)
              • Biochemical assisted hatching(BAH) increased the implantation and pregnancy rate in human cryopreserved embryo transfer. (55h ASRM, 1999)
              • Implantation Regulation of integrin a1, av, and b3 gene expression by leukemia inhibitory factor(LIF) during blastocyst outgrowth in the mouse.(30th SSR, 1997)
                • ART
                  • Hatching and outgrowth according to various freezing procedures in mouse blastocyst cryopreservation. (12th ESHRE, 1996)
                  • Pregnancy from Translocation carrier patient with recurrent abortion by preimplantation genetic diagnosis using fluorescence in-situ hybridization. (52th ASRM, 1996)
                  • Assisted Reproductive Technology Program by Immature Oocyte Retrieval in Non-stimulated Cycle (54th ASRM, 1998)
                  • Clinical use of immature oocyte from normal and PCO women in non-stimulated IVF-ET program. (55th ASRM, 1999)
                  • Fragmentation of embryos is associated with both necrosis and apoptosis. (Fertil Steril 2011).
                  ROS (Reactive Oxygen Species)
                  • Effect of the antioxidant supplemented into semen or sperm washing medium on functional parameter of human spermatozoa (KSFS 2006, Hum Reprod 2008)
                  • Correlation between seminal parameter of patients and sperm DNA fragmentation estimated by comet assay (KSFS 2006, CERM 2011)
                  • Detection of oxidative stress on sperm by using Oxisperm kit
                    • Genetics
                      Cytogenetics
                      • Amniotic fluid
                      • Chorionic villi cells
                      • Peripheral blood/ Cord blood
                      • Tissue
                      Molecular genetics
                      • Preimplantation genetic diagnosis (PGD, FISH)
                      • Preimplantation genetic screening (PGS, FISH)
                      • Azoospermia related gene test (Daz test)
                      • Amniotic fluid FISH (18, 21)